The CNN Health has a detailed article on the quest for longer-lasting Covid-19 vaccines, which has been discussion recently due emerging variants of the Covid-19 around the world. It writes “to maintain durable protection against the virus that causes Covid-19, scientists are working around the clock to develop next-generation vaccines. But some of the nuances around why and how immunity against Covid-19 fades remain a mystery.”

Scientists are reportedly trying to understand the “Covid immunity nuances” especially “whether some of this drop off in our protection may be a result of the mRNA technology used to build some Covid-19 vaccines, such as those developed by Moderna and Pfizer/BioNTech, which were the first in the world to use this platform”.

Some vaccine platforms give a very high degree of protection but the durability isn’t very long. The mRNA platform may be one of those.

– Dr. Anthony Fauci, director of the National Institutes of Allergy and Infectious Diseases (source: CNN)

Dr Fauci told to CNN “We got a really great platform with mRNA. But let’s try to be better. Because our experience, maybe it’s peculiar to coronavirus, but I doubt it, is that the durability of the response you can be better on.”

“We have very good vaccines, but we’ve got to get better platforms and immunogens, maybe with adjuvants that allow us to have a greater durability of protection. Adjuvants are extra ingredients in vaccines that help them work better, Fauci added.

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Other experts see to agree with Dr Fauci’s view. Dr. Deepta Bhattacharya, head of a lab at the University of Arizona, told CNN “There have been a few side-by-side studies that have compared the mRNA vaccines to infection-induced immunity, and it seems like it slips a little bit faster than that. […] I do think it’s fair to ask more of our vaccines and that they sort of maintain that protection for longer. I think there’s still very clearly room for improvement because there are certain vaccines that do better in terms of their durability. There’s no question about that.”